• product_banner

8 Year Exporter Aat - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

We insist on the principle of development of 'High quality, Efficiency, Sincerity and Down-to-earth working approach' to provide you with excellent service of processing for H Pylori Igm Antibody, Hcg Pregnancy Test, Rapid Diagnostic Test For Dengue, We intention at Ongoing system innovation, management innovation, elite innovation and market place innovation, give full play into the overall advantages, and frequently strengthen services excellent.
8 Year Exporter Aat - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody Detail:

Product details

General Information
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

Properties

Pair Recommendation CLIA (Capture-Detection):
1D5-5 ~ 3G11-6
1D12-2 ~ 1G3-7
Purity >95% as determined by SDS-PAGE.
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

DETAIL (2)
DETAIL (1)

Order Information

Product Name Cat. No Clone ID
TIMP1 AB0034-1 1D5-5
AB0034-2 1D12-2
AB0034-3 1G3-7
AB0034-4 3G11-6

Note: Bioantibody can customized quantities per your need.

Citations

1.Barylski M , Kowalczyk E , Szadkowska I , et al. [Tissue inhibitor of metalloproteinases[J]. Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.

2.Hayakawa T , Yamashita K , Tanzawa K , et al. Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum[J]. FEBS Letters, 1992, 298.

3.Haider D G , Karin S , Gerhard P , et al. Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects.[J]. Journal of Clinical Endocrinology & Metabolism(3):1168-71.


Product detail pictures:

8 Year Exporter Aat - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures

8 Year Exporter Aat - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures


Related Product Guide:

We take pleasure in a really excellent name amongst our shoppers for our exceptional product or service excellent, competitive rate and also the greatest services for 8 Year Exporter Aat - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Vietnam, Brasilia, Swansea, Our company absorbs new ideas, strict quality control, a full range of service tracking, and adhere to make high-quality products. Our business aims to "honest and trustworthy, favorable price, customer first", so we won the trust of the majority of customers! If you are interested in our products and services, please do not hesitate to contact us!
  • It is not easy to find such a professional and responsible provider in today's time. Hope that we can maintain long-term cooperation.
    5 Stars By Alexander from The Swiss - 2017.07.28 15:46
    After the signing of the contract, we received satisfactory goods in a short term, this is a commendable manufacturer.
    5 Stars By Giselle from Turin - 2017.09.28 18:29
    Write your message here and send it to us