Anti-human GH Antibody, Mouse Monoclonal

General Information
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in human and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.

GH tests are used to diagnose GH disorders, including:
★ GH deficiency. In children, GH is essential for normal growth and development. A GH deficiency can cause a child to grow more slowly and be much shorter than children of the same age. In adults, GH deficiency can lead to low bone density and reduced muscle mass.
★ Gigantism. This is a rare childhood disorder that causes the body to produce too much GH. Children with gigantism are very tall for their age and have large hands and feet.
★ Acromegaly. This disorder, which affects adults, causes the body to produce too much growth hormone. Adults with acromegaly have thicker than normal bones and enlarged hands, feet, and facial features.