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Best Price on Brucella Ab - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody

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Best Price on Brucella Ab - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.

Properties

Pair Recommendation CLIA (Capture-Detection):
1E5-1 ~ 1D6-10
1E5-1 ~ 1E6-7
Purity >95%, determined by SDS-PAGE
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

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Order Information

Product Name Cat. No Clone ID
PIVKA-Ⅱ AB0009-1 1F4-5
AB0009-2 1E5-1
AB0009-3 1D6-10
AB0009-4 1E6-7

Note: Bioantibody can customized quantities per your need.

Citations

1.Matsueda K , Yamamoto H , Yoshida Y , et al. Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist II (PIVKA-II) and α-fetoprotein (AFP)[J]. Journal of Gastroenterology, 2006, 41(10):1011-1019.

2.Viggiani, Valentina, Palombi,等. Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients.[J]. Scandinavian Journal of Gastroenterology, 2016.

3.Simundic A M . Practical recommendations for statistical analysis and data presentation in Biochemia Medica journal[J]. Biochemia Medica, 2012, 22(1).

4.Tartaglione S , Pecorella I , Zarrillo S R , et al. Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study[J]. Biochemia Medica, 2019, 29(2).


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Best Price on Brucella Ab - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures

Best Price on Brucella Ab - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures


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We strive for excellence, services the customers", hopes to be the top cooperation team and dominator business for personnel, suppliers and prospects, realizes benefit share and continual promotion for Best Price on Brucella Ab - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Jamaica, Curacao, Malawi, We pay high attention to customer service, and cherish every customer. We've maintained a strong reputation in the industry for many years. We are honest and work on building a long-term relationship with our customers.
  • The company can keep up with the changes in this industry market, product updates fast and the price is cheap, this is our second cooperation, it's good.
    5 Stars By Janet from Slovenia - 2017.12.09 14:01
    The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.
    5 Stars By Michelle from Muscat - 2018.12.22 12:52
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