Best-Selling Dual Antigen Test For Malaria - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody
Best-Selling Dual Antigen Test For Malaria - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody Detail:
Product details
General Information
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.
Properties
| Pair Recommendation |
CLIA (Capture-Detection): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | PBS, pH7.4 |
| Storage |
Store it under sterile conditions at -20℃ to -80℃ upon receiving. For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles. |
Comparison Analysis
| Bioantibody | clinically diagnosed case | Total | |
| positive | Negative | ||
| positive | 46 | 3 | 49 |
| Negative | 4 | 97 | 101 |
| Total | 50 | 100 | 150 |
| evaluation index | sensitivity | specificity | accuracy |
| 92% | 97% | 95% | |
Order Information
| Product Name | Cat. No | Clone ID |
| CHI3L1 | AB0031-1 | 1G11-14 |
| AB0031-2 | 2E4-2 | |
| AB0031-3 | 3A12-1 | |
| AB0031-4 | 13F3-1 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al. Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children[J]. Metabolism-clinical & Experimental, 2012, 61(4):562-568.
2.Yu-Huan M , Li-Ming T , Jian-Ying L I , et al. Evaluation on application of serum chitinase-3-like protein 1,alpha-fetoprotein and ferritin detection to diagnosing hepatocellular carcinoma[J]. Practical Preventive Medicine, 2018.
Product detail pictures:
Related Product Guide:
Our items are commonly identified and trusted by customers and may fulfill continuously switching economic and social wants of Best-Selling Dual Antigen Test For Malaria - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody , The product will supply to all over the world, such as: belarus, New Zealand, Melbourne, Profession, Devoting are always fundamental to our mission. We have always been in line with serving customers, creating value management objectives and adhering to the sincerity, dedication, persistent management idea.
By Lesley from Amman - 2018.12.22 12:52
Problems can be quickly and effectively resolved, it is worth to be trust and working together.
By Erica from Doha - 2018.02.04 14:13
