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Best-Selling Occult Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody

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Best-Selling Occult Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Properties

Pair Recommendation CLIA (Capture-Detection):
23F1-5 ~ 6C1-9
23F1-5 ~ 3A2-1
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
GDF-15 AB0038-1 3A2-1
AB0038-2 23F1-5
AB0038-3 6C1-9
AB0038-4 4D5-8

Note: Bioantibody can customized quantities per your need.

Citations

1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.

2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.


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Best-Selling Occult Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Best-Selling Occult Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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In order to best meet client's needs, all of our operations are strictly performed in line with our motto "High Quality, Competitive Price, Fast Service" for Best-Selling Occult Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Guatemala, Switzerland, Ukraine, Now, we professionally supplies customers with our main products And our business is not only the "buy" and "sell", but also focus on more. We target to be your loyal supplier and long-term cooperator in China. Now, We hope to be the friends with you.
  • The customer service staff's answer is very meticulous, the most important is that the product quality is very good, and packaged carefully, shipped quickly!
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