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China Factory for Calprotectin - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody

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China Factory for Calprotectin - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Properties

Pair Recommendation CLIA (Capture-Detection):
23F1-5 ~ 6C1-9
23F1-5 ~ 3A2-1
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
GDF-15 AB0038-1 3A2-1
AB0038-2 23F1-5
AB0038-3 6C1-9
AB0038-4 4D5-8

Note: Bioantibody can customized quantities per your need.

Citations

1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.

2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.


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China Factory for Calprotectin - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures

China Factory for Calprotectin - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Well-run products, skilled income group, and better after-sales products and services; We have been also a unified massive family, all people stick with the business price "unification, dedication, tolerance" for China Factory for Calprotectin - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Russia, Canada, United Arab emirates, We've got more than 10 years experience of production and export business. We always develop and design kinds of novel items to meet the market demand and help the guests continuously by updating our goods. We've been specialized manufacturer and exporter in China. Wherever you are, make sure you join us, and together we will shape a bright future in your business field!
  • We have been engaged in this industry for many years, we appreciate the work attitude and production capacity of the company, this is a reputable and professional manufacturer.
    5 Stars By Sara from Mauritania - 2018.12.25 12:43
    It is a very good, very rare business partners, looking forward to the next more perfect cooperation!
    5 Stars By Belle from Azerbaijan - 2017.11.12 12:31
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