• product_banner

China Factory for Calprotectin - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

Sticking to the principle of "Super High-quality, Satisfactory service" ,We are striving to generally be a very good business partner of you for Test Antigen Saliva, Hemoglobin In Stool Test, Rapid Test Swab Antigen, We have been wanting forwards to creating long-term company interactions with around the world shoppers.
China Factory for Calprotectin - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody Detail:

Product details

General Information
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

Properties

Pair Recommendation CLIA (Capture-Detection):
1D5-5 ~ 3G11-6
1D12-2 ~ 1G3-7
Purity >95% as determined by SDS-PAGE.
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

DETAIL (2)
DETAIL (1)

Order Information

Product Name Cat. No Clone ID
TIMP1 AB0034-1 1D5-5
AB0034-2 1D12-2
AB0034-3 1G3-7
AB0034-4 3G11-6

Note: Bioantibody can customized quantities per your need.

Citations

1.Barylski M , Kowalczyk E , Szadkowska I , et al. [Tissue inhibitor of metalloproteinases[J]. Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.

2.Hayakawa T , Yamashita K , Tanzawa K , et al. Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum[J]. FEBS Letters, 1992, 298.

3.Haider D G , Karin S , Gerhard P , et al. Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects.[J]. Journal of Clinical Endocrinology & Metabolism(3):1168-71.


Product detail pictures:

China Factory for Calprotectin - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures

China Factory for Calprotectin - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures


Related Product Guide:

Our crew through skilled training. Skilled skilled knowledge, strong sense of company, to meet the company wants of customers for China Factory for Calprotectin - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Florence, Nepal, Austria, With a team of experienced and knowledgeable personnel, our market covers South America, the USA, the Mid East, and North Africa. Many customers have become our friends after good cooperation with us. If you have the requirement for any of our goods, make sure you contact us now. We're looking forward to hearing from you soon.
  • The factory workers have rich industry knowledge and operational experience, we learned a lot in working with them,we are extremely grateful that we can encount a good company has excellent wokers.
    5 Stars By Molly from New York - 2018.06.30 17:29
    We are old friends, the company's product quality has been always very good and this time the price is also very cheap.
    5 Stars By Doreen from Croatia - 2017.06.25 12:48
    Write your message here and send it to us