China Manufacturer for Occult Stool Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody

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China Manufacturer for Occult Stool Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.

Properties

Pair Recommendation	CLIA (Capture-Detection): 1E5-1 ~ 1D6-10 1E5-1 ~ 1E6-7
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

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Order Information

Product Name	Cat. No	Clone ID
PIVKA-Ⅱ	AB0009-1	1F4-5
	AB0009-2	1E5-1
	AB0009-3	1D6-10
	AB0009-4	1E6-7

Note: Bioantibody can customized quantities per your need.

Citations

1.Matsueda K , Yamamoto H , Yoshida Y , et al. Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist II (PIVKA-II) and α-fetoprotein (AFP)[J]. Journal of Gastroenterology, 2006, 41(10):1011-1019.

2.Viggiani, Valentina, Palombi,等. Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients.[J]. Scandinavian Journal of Gastroenterology, 2016.

3.Simundic A M . Practical recommendations for statistical analysis and data presentation in Biochemia Medica journal[J]. Biochemia Medica, 2012, 22(1).

4.Tartaglione S , Pecorella I , Zarrillo S R , et al. Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study[J]. Biochemia Medica, 2019, 29(2).

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Our business aims to operating faithfully, serving to all of our clients , and working in new technology and new machine continuously for China Manufacturer for Occult Stool Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Brunei, United States, Islamabad, Our company insists on the purpose of "takes service priority for standard, quality guarantee for the brand, do business in good faith, to provide professional, rapid, accurate and timely service for you". We welcome old and new customers to negotiate with us. We will serve you with all sincerity!

Abnormal Occult Blood Test