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China OEM Helico Pylori Antibody - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody

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China OEM Helico Pylori Antibody - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.

Properties

Pair Recommendation CLIA (Capture-Detection):
1E5-1 ~ 1D6-10
1E5-1 ~ 1E6-7
Purity >95%, determined by SDS-PAGE
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

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Order Information

Product Name Cat. No Clone ID
PIVKA-Ⅱ AB0009-1 1F4-5
AB0009-2 1E5-1
AB0009-3 1D6-10
AB0009-4 1E6-7

Note: Bioantibody can customized quantities per your need.

Citations

1.Matsueda K , Yamamoto H , Yoshida Y , et al. Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist II (PIVKA-II) and α-fetoprotein (AFP)[J]. Journal of Gastroenterology, 2006, 41(10):1011-1019.

2.Viggiani, Valentina, Palombi,等. Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients.[J]. Scandinavian Journal of Gastroenterology, 2016.

3.Simundic A M . Practical recommendations for statistical analysis and data presentation in Biochemia Medica journal[J]. Biochemia Medica, 2012, 22(1).

4.Tartaglione S , Pecorella I , Zarrillo S R , et al. Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study[J]. Biochemia Medica, 2019, 29(2).


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China OEM Helico Pylori Antibody - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures

China OEM Helico Pylori Antibody - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Our eternal pursuits are the attitude of "regard the market, regard the custom, regard the science" as well as theory of "quality the basic, have faith in the initial and administration the advanced" for China OEM Helico Pylori Antibody - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Vietnam, Bangladesh, Haiti, We are seeking the chances to meet all the friends from both at home and abroad for the win-win cooperation. We sincerely hope to have long-term cooperation with all of you on the bases of mutual benefit and common development.
  • Goods just received, we are very satisfied, a very good supplier, hope to make persistent efforts to do better.
    5 Stars By Giselle from Curacao - 2018.02.21 12:14
    Good quality, reasonable prices, rich variety and perfect after-sales service, it's nice!
    5 Stars By Jo from Luxemburg - 2017.09.09 10:18
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