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Chinese Professional Antigen Ag Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody

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Chinese Professional Antigen Ag Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Properties

Pair Recommendation CLIA (Capture-Detection):
23F1-5 ~ 6C1-9
23F1-5 ~ 3A2-1
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
GDF-15 AB0038-1 3A2-1
AB0038-2 23F1-5
AB0038-3 6C1-9
AB0038-4 4D5-8

Note: Bioantibody can customized quantities per your need.

Citations

1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.

2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.


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Chinese Professional Antigen Ag Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Chinese Professional Antigen Ag Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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We attempt for excellence, support the customers", hopes to become the top cooperation team and dominator enterprise for staff, suppliers and shoppers, realizes worth share and continual marketing for Chinese Professional Antigen Ag Test - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Turkey, Slovenia, Macedonia, We confirm to public, cooperation, win-win situation as our principle, adhere to the philosophy of make a living by quality, keep developing by honesty , sincerely hope to build up a good relationship with more and more customers and friends, to achieve a win-win situation and common prosperity.
  • The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.
    5 Stars By Phoebe from Peru - 2017.11.11 11:41
    The company keeps to the operation concept "scientific management, high quality and efficiency primacy, customer supreme", we have always maintained business cooperation. Work with you,we feel easy!
    5 Stars By Agnes from Croatia - 2017.01.11 17:15
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