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Europe style for Chikungunya Igm Positive Means - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody

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General Information
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.

Properties

Pair Recommendation CLIA (Capture-Detection):
11G11-6 ~ 8A3-9
11G11-6 ~ 5B9-4
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
MMP-3 AB0025-1 11G11-6
AB0025-2 8A3-9
AB0025-3 5B9-4

Note: Bioantibody can customized quantities per your need.

Citations

1.Yamanaka H , Matsuda Y , Tanaka M , et al. Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritis[J]. Arthrits & Rheumatism, 2000, 43(4):852–858.

2.Hattori Y , Kida D , Kaneko A . Normal serum matrix metalloproteinase-3 levels can be used to predict clinical remission and normal physical function in patients with rheumatoid arthritis[J]. Clinical Rheumatology, 2018.


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Europe style for Chikungunya Igm Positive Means - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Europe style for Chikungunya Igm Positive Means - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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We depend on sturdy technical force and continually create sophisticated technologies to meet the demand of Europe style for Chikungunya Igm Positive Means - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Portugal, Morocco, Greek, We are proud to supply our products and solutions to every costumer all around the world with our flexible, fast efficient services and strictest quality control standard which has always approved and praised by customers.
  • The supplier cooperation attitude is very good, encountered various problems, always willing to cooperate with us, to us as the real God.
    5 Stars By Gail from Porto - 2017.09.26 12:12
    Superb technology, perfect after-sales service and efficient work efficiency, we think this is our best choice.
    5 Stars By Belle from Philadelphia - 2018.06.26 19:27
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