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Factory Cheap Antigen Detection Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody

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Factory Cheap Antigen Detection Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody Detail:

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General Information
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.

Properties

Pair Recommendation CLIA (Capture-Detection):
2E4-2 ~ 1G11-14
13F3-1 ~ 1G11-14
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

Bioantibody clinically diagnosed case Total
positive Negative
positive 46 3 49
Negative 4 97 101
Total 50 100 150
evaluation index sensitivity specificity accuracy
92% 97% 95%

Order Information

Product Name Cat. No Clone ID
CHI3L1 AB0031-1 1G11-14
AB0031-2 2E4-2
AB0031-3 3A12-1
AB0031-4 13F3-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al. Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children[J]. Metabolism-clinical & Experimental, 2012, 61(4):562-568.

2.Yu-Huan M , Li-Ming T , Jian-Ying L I , et al. Evaluation on application of serum chitinase-3-like protein 1,alpha-fetoprotein and ferritin detection to diagnosing hepatocellular carcinoma[J]. Practical Preventive Medicine, 2018.


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Factory Cheap Antigen Detection Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody detail pictures

Factory Cheap Antigen Detection Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody detail pictures


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Our company sticks to the principle of "Quality is the life of the company, and reputation is the soul of it" for Factory Cheap Antigen Detection Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody , The product will supply to all over the world, such as: Argentina, Cancun, Puerto Rico, The credibility is the priority, and the service is the vitality. We promise we have the ability to provide excellent quality and reasonable price products for customers. With us, your safety is guaranteed.
  • In China, we have purchased many times, this time is the most successful and most satisfactory, a sincere and realiable Chinese manufacturer!
    5 Stars By Norma from Grenada - 2018.04.25 16:46
    This manufacturers not only respected our choice and requirements, but also gave us a lot of good suggestions, ultimately, we successfully completed the procurement tasks.
    5 Stars By Gary from Wellington - 2017.08.21 14:13
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