Factory Outlets Cd16a Protein - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody
Factory Outlets Cd16a Protein - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension and proteinuria after 20 weeks of gestation. Preeclampsia occurs in 3‑5 % of pregnancies and results in substantial maternal and fetal or neonatal mortality and morbidity. Clinical manifestations can vary from mild to severe forms; preeclampsia is still one of the leading causes of fetal and maternal morbidity and mortality.
Preeclampsia appears to be due to the release of angiogenic factors from the placenta that induces endothelial dysfunction. Serum levels of PlGF (placental growth factor) and sFlt‑1 (soluble fms‑like tyrosine kinase‑1, also known as soluble VEGF receptor‑1) are altered in women with preeclampsia. Moreover, circulating levels of PlGF and sFlt‑1 can discriminate normal pregnancy from preeclampsia even before clinical symptoms occur. In normal pregnancy, the pro‑angiogenic factor PlGF increases during the first two trimesters and decreases as pregnancy progresses to term. In contrast, levels of the anti-angiogenic factor sFlt‑1 remain stable during the early and middle stages of gestation and increase steadily until term. In women who develop preeclampsia, sFlt‑1 levels have been found to be higher and PlGF levels have been found to be lower than in normal pregnancy.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
| Purity | >95% as determined by SDS-PAGE. |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Order Information
| Product Name | Cat. No | Clone ID |
| PLGF | AB0036-1 | 7G1-2 |
| AB0036-2 | 5D9-3 | |
| AB0036-3 | 5G7-1 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Brown MA, Lindheimer MD, de Swiet M, et al. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 2001;20(1):IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, et al. Pre-eclampsia: pathophysiology, diagnosis, and management. Vasc Health Risk Manag 2011;7:467-474.
Product detail pictures:
Related Product Guide:
With the "Client-Oriented" business philosophy, a rigorous quality control system, advanced manufacturing equipment and a strong R&D team, we always provide high quality products, excellent services and competitive prices for Factory Outlets Cd16a Protein - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Johor, Macedonia, Tunisia, We warmly welcome your patronage and will serve our clients both at home and abroad with products and solutions of superior quality and excellent service geared to the trend of further development as always. We believe you will benefit from our professionalism soon.
By Delia from Slovenia - 2017.11.29 11:09
The customer service staff is very patient and has a positive and progressive attitude to our interest, so that we can have a comprehensive understanding of the product and finally we reached an agreement, thanks!
By Agustin from Durban - 2018.09.23 17:37
