Factory source Avp - Anti-human calprotectin Antibody, Mouse Monoclonal – Bioantibody

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General Information
Calprotectin is a protein released by a type of white blood cell called a neutrophil. When there is inflammation in the gastrointestinal (GI) tract, neutrophils move to the area and release calprotectin, resulting in an increased level in the stool. Measuring the level of calprotectin in stool is a useful way to detect inflammation in the intestines.
Intestinal inflammation is associated with inflammatory bowel disease (IBD) and with some bacterial GI infections, but it is not associated with many other disorders that affect bowel function and cause similar symptoms. Calprotectin can be used to help distinguish between inflammatory and non-inflammatory conditions, as well as monitoring disease activity.

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Citations

1. Rowe, W. and Lichtenstein, G. (2016 June 17 Updated). Inflammatory Bowel Disease Workup. Medscape Drugs and Diseases. Available online at http://emedicine.medscape.com/article/179037-workup#c6. Accessed on 1/22/17.

2. Walsham, N. and Sherwood, R. (2016 January 28). Fecal calprotectin in inflammatory bowel disease. Clin Exp Gastroenterol. 2016; 9: 21–29. Available online at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734737/ Accessed on 1/22/17.

3. Douglas, D. (2016 January 04). Fecal Calprotectin Level Not Consistent in IBD. Reuters Health Information. Available online at http://www.medscape.com/viewarticle/856661. Accessed on 1/22/17.

4. Zhulina, Y. et. al. (2016). The Prognostic Significance of Faecal Calprotectin in Patients With Inactive Inflammatory Bowel Disease. Aliment Pharmacol Ther. 2016;44(5):495-504. Available online at http://www.medscape.com/viewarticle/867381. Accessed on 1/22/17.

5. Caccaro, R. et. al. (2012). Clinical Utility of Calprotectin and Lactoferrin in Patients With Inflammatory Bowel Disease. Medscape Today News from Expert Rev Clin Immunol v8

6. 579-585 [On-line information]. Available online at http://www.medscape.com/viewarticle/771596. Accessed February 2013.