General Information
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in human and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.
GH tests are used to diagnose GH disorders, including:
★ GH deficiency. In children, GH is essential for normal growth and development. A GH deficiency can cause a child to grow more slowly and be much shorter than children of the same age. In adults, GH deficiency can lead to low bone density and reduced muscle mass.
★ Gigantism. This is a rare childhood disorder that causes the body to produce too much GH. Children with gigantism are very tall for their age and have large hands and feet.
★ Acromegaly. This disorder, which affects adults, causes the body to produce too much growth hormone. Adults with acromegaly have thicker than normal bones and enlarged hands, feet, and facial features.
Pair Recommendation | CLIA (Capture-Detection): 7F5-2 ~ 8C7-10 |
Purity | / |
Buffer Formulation | / |
Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Product Name | Cat. No | Clone ID |
GH | AB0077-1 | 7F5-2 |
AB0077-2 | 8C7-10 | |
AB0077-3 | 2A4-1 | |
AB0077-4 | 2E12-6 | |
AB0077-5 | 6F11-8 |
Note: Bioantibody can customized quantities per your need.
1. Ranabir S, Reetu K (January 2011). “Stress and hormones”. Indian Journal of Endocrinology and Metabolism. 15 (1): 18–22. doi:10.4103/2230-8210.77573. PMC 3079864. PMID 21584161.
2. Greenwood FC, Landon J (April 1966). “Growth hormone secretion in response to stress in man”. Nature. 210 (5035): 540–1. Bibcode:1966Natur.210..540G. doi:10.1038/210540a0. PMID 5960526. S2CID 1829264.