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Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody

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Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension and proteinuria after 20 weeks of gestation. Preeclampsia occurs in 3‑5 % of pregnancies and results in substantial maternal and fetal or neonatal mortality and morbidity. Clinical manifestations can vary from mild to severe forms; preeclampsia is still one of the leading causes of fetal and maternal morbidity and mortality.

Preeclampsia appears to be due to the release of angiogenic factors from the placenta that induces endothelial dysfunction. Serum levels of PlGF (placental growth factor) and sFlt‑1 (soluble fms‑like tyrosine kinase‑1, also known as soluble VEGF receptor‑1) are altered in women with preeclampsia. Moreover, circulating levels of PlGF and sFlt‑1 can discriminate normal pregnancy from preeclampsia even before clinical symptoms occur. In normal pregnancy, the pro‑angiogenic factor PlGF increases during the first two trimesters and decreases as pregnancy progresses to term. In contrast, levels of the anti-angiogenic factor sFlt‑1 remain stable during the early and middle stages of gestation and increase steadily until term. In women who develop preeclampsia, sFlt‑1 levels have been found to be higher and PlGF levels have been found to be lower than in normal pregnancy.

Properties

Pair Recommendation  
CLIA (Capture-Detection):
7G1-2 ~ 5D9-3
5D9-3 ~ 7G1-2
Purity >95% as determined by SDS-PAGE.
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
PLGF AB0036-1 7G1-2
AB0036-2 5D9-3
AB0036-3 5G7-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Brown MA, Lindheimer MD, de Swiet M, et al. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 2001;20(1):IX-XIV.

2.Uzan J, Carbonnel M, Piconne O, et al. Pre-eclampsia: pathophysiology, diagnosis, and management. Vasc Health Risk Manag 2011;7:467-474.


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Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody detail pictures

Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Sticking for the basic principle of "Super Top quality, Satisfactory service" ,We've been striving to be an excellent business enterprise partner of you for Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Armenia, United States, Colombia, We've got constantly insisted on the evolution of solutions, spent good funds and human resource in technological upgrading, and facilitate production improvement, meeting the wants of prospects from all countries and regions.
  • The goods are very perfect and the company sales manager is warmful, we will come to this company to purchase next time.
    5 Stars By Arabela from United States - 2017.07.28 15:46
    This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
    5 Stars By Jessie from Bahamas - 2017.11.29 11:09
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