Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody
Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension and proteinuria after 20 weeks of gestation. Preeclampsia occurs in 3‑5 % of pregnancies and results in substantial maternal and fetal or neonatal mortality and morbidity. Clinical manifestations can vary from mild to severe forms; preeclampsia is still one of the leading causes of fetal and maternal morbidity and mortality.
Preeclampsia appears to be due to the release of angiogenic factors from the placenta that induces endothelial dysfunction. Serum levels of PlGF (placental growth factor) and sFlt‑1 (soluble fms‑like tyrosine kinase‑1, also known as soluble VEGF receptor‑1) are altered in women with preeclampsia. Moreover, circulating levels of PlGF and sFlt‑1 can discriminate normal pregnancy from preeclampsia even before clinical symptoms occur. In normal pregnancy, the pro‑angiogenic factor PlGF increases during the first two trimesters and decreases as pregnancy progresses to term. In contrast, levels of the anti-angiogenic factor sFlt‑1 remain stable during the early and middle stages of gestation and increase steadily until term. In women who develop preeclampsia, sFlt‑1 levels have been found to be higher and PlGF levels have been found to be lower than in normal pregnancy.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
| Purity | >95% as determined by SDS-PAGE. |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Order Information
| Product Name | Cat. No | Clone ID |
| PLGF | AB0036-1 | 7G1-2 |
| AB0036-2 | 5D9-3 | |
| AB0036-3 | 5G7-1 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Brown MA, Lindheimer MD, de Swiet M, et al. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 2001;20(1):IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, et al. Pre-eclampsia: pathophysiology, diagnosis, and management. Vasc Health Risk Manag 2011;7:467-474.
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Our primary objective is usually to offer our shoppers a serious and responsible small business relationship, offering personalized attention to all of them for Good Quality Antibody Drug - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Indonesia, Jordan, Honduras, Most problems between suppliers and clients are due to poor communication. Culturally, suppliers can be reluctant to question items they do not understand. We break down people barriers to ensure you get what you want to the level you expect, when you want it. Faster delivery time and the product you want is our Criterion .
By Odelette from Argentina - 2017.09.30 16:36
The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.
By Cherry from Eindhoven - 2017.05.02 18:28
