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Good Quality C Reactive Protein - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody

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Good Quality C Reactive Protein - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.

Properties

Pair Recommendation CLIA (Capture-Detection):
1E5-1 ~ 1D6-10
1E5-1 ~ 1E6-7
Purity >95%, determined by SDS-PAGE
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

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Order Information

Product Name Cat. No Clone ID
PIVKA-Ⅱ AB0009-1 1F4-5
AB0009-2 1E5-1
AB0009-3 1D6-10
AB0009-4 1E6-7

Note: Bioantibody can customized quantities per your need.

Citations

1.Matsueda K , Yamamoto H , Yoshida Y , et al. Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist II (PIVKA-II) and α-fetoprotein (AFP)[J]. Journal of Gastroenterology, 2006, 41(10):1011-1019.

2.Viggiani, Valentina, Palombi,等. Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients.[J]. Scandinavian Journal of Gastroenterology, 2016.

3.Simundic A M . Practical recommendations for statistical analysis and data presentation in Biochemia Medica journal[J]. Biochemia Medica, 2012, 22(1).

4.Tartaglione S , Pecorella I , Zarrillo S R , et al. Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study[J]. Biochemia Medica, 2019, 29(2).


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Good Quality C Reactive Protein - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures

Good Quality C Reactive Protein - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures


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"Quality first, Honesty as base, Sincere service and mutual profit" is our idea, in order to develop continuously and pursue the excellence for Good Quality C Reactive Protein - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Ecuador, Johor, Portugal, We rely on high-quality materials, perfect design, excellent customer service and the competitive price to win the trust of many customers at home and abroad. 95%products are exported to overseas markets.
  • This company has a lot of ready-made options to choose and also could custom new program according to our demand, which is very nice to meet our needs.
    5 Stars By Steven from San Francisco - 2017.11.29 11:09
    The goods we received and the sample sales staff display to us have the same quality, it is really a creditable manufacturer.
    5 Stars By Eunice from Bhutan - 2018.09.23 17:37
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