Good User Reputation for Stool Guaiac Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody
Good User Reputation for Stool Guaiac Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.
Properties
| Pair Recommendation |
CLIA (Capture-Detection): 1E5-1 ~ 1D6-10 1E5-1 ~ 1E6-7 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles. |
Comparison Analysis
Order Information
| Product Name | Cat. No | Clone ID |
| PIVKA-Ⅱ | AB0009-1 | 1F4-5 |
| AB0009-2 | 1E5-1 | |
| AB0009-3 | 1D6-10 | |
| AB0009-4 | 1E6-7 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Matsueda K , Yamamoto H , Yoshida Y , et al. Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist II (PIVKA-II) and α-fetoprotein (AFP)[J]. Journal of Gastroenterology, 2006, 41(10):1011-1019.
2.Viggiani, Valentina, Palombi,等. Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients.[J]. Scandinavian Journal of Gastroenterology, 2016.
3.Simundic A M . Practical recommendations for statistical analysis and data presentation in Biochemia Medica journal[J]. Biochemia Medica, 2012, 22(1).
4.Tartaglione S , Pecorella I , Zarrillo S R , et al. Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study[J]. Biochemia Medica, 2019, 29(2).
Product detail pictures:
Related Product Guide:
The really abundant projects management experiences and 1 to just one provider model make the high importance of business enterprise communication and our easy understanding of your expectations for Good User Reputation for Stool Guaiac Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Miami, Finland, Southampton, "Good quality and reasonable price" are our business principles. If you are interested in our products or have any questions, make sure you feel free to contact us. We hope to establish cooperative relationships with you in the near future.
By Judith from Manila - 2018.09.21 11:44
It is really lucky to meet such a good supplier, this is our most satisfied cooperation, I think we will work again!
By Rigoberto Boler from Italy - 2017.03.08 14:45
