High definition Test Kit Antigen - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody
High definition Test Kit Antigen - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Pepsinogen I, the precursors of pepsin, is produced by the gastric mucosa and released into the gastric lumen and peripheral circulation. Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kD. PG I (isoenzyme 1-5) is secreted mainly by chief cells in the fundic mucosa, whereas PG II (isoenzyme 6-7) is secreted by the pyloric glands and the proximal duodenal mucosa.
Precursor reflects numbers of stomach surface cells as well as glandular cells, and monitors gastric atrophy indirectly. They are also extraordinarily stable because they perform their jobs under the harsh conditions present in the digestive system. The atrophy of the corpus mucosa leads to low synthesis of pepsinogen I and hence its low release into the serum. Serum pepsinogen I indicates function and states of gastric mucosa.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 1C1-3 ~ 1G7-3 1E3-1 ~ 1G7-3 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Comparison Analysis
Order Information
| Product Name | Cat. No | Clone ID |
| PGI | AB0005-1 | 1C1-3 |
| AB0005-2 | 1E3-1 | |
| AB0005-3 | 1G7-3 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Sipponen P , Ranta P , Helske T , et al. Serum levels of amidated gastrin-17 and pepsinogen I in atrophic gastritis: an observational case-control study.[J]. Scandinavian Journal of Gastroenterology, 2002, 37(7):785-791.
2.Mangla J C , Schenk E A , Desbaillets L , et al. Pepsin secretion, pepsinogen, and gastrin in Barrett’s esophagus’. Clinical and morphological characteristics[J]. Gastroenterology, 1976, 70(5 PT.1):669-676.
Product detail pictures:
Related Product Guide:
With responsible good quality method, good status and excellent client services, the series of solutions produced by our company are exported to lots of countries and regions for High definition Test Kit Antigen - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Austria, New Delhi, United Arab emirates, We believe that good business relationships will lead to mutual benefits and improvement for both parties. We now have established long-term and successful cooperative relationships with many customers through their confidence in our customized services and integrity in doing business. We also enjoy a high reputation through our good performance. Better performance will be expected as our principle of integrity. Devotion and Steadiness will remain as ever.
By Julia from Guinea - 2017.08.18 11:04
Company director has very rich management experience and strict attitude, sales staff are warm and cheerful, technical staff are professional and responsible,so we have no worry about product,a nice manufacturer.
By Aaron from Nepal - 2018.09.19 18:37
