High Performance Test For Blood In Stool - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody
High Performance Test For Blood In Stool - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 1E5-1 ~ 1D6-10 1E5-1 ~ 1E6-7 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles. |
Comparison Analysis
Order Information
| Product Name | Cat. No | Clone ID |
| PIVKA-Ⅱ | AB0009-1 | 1F4-5 |
| AB0009-2 | 1E5-1 | |
| AB0009-3 | 1D6-10 | |
| AB0009-4 | 1E6-7 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Matsueda K , Yamamoto H , Yoshida Y , et al. Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist II (PIVKA-II) and α-fetoprotein (AFP)[J]. Journal of Gastroenterology, 2006, 41(10):1011-1019.
2.Viggiani, Valentina, Palombi,等. Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients.[J]. Scandinavian Journal of Gastroenterology, 2016.
3.Simundic A M . Practical recommendations for statistical analysis and data presentation in Biochemia Medica journal[J]. Biochemia Medica, 2012, 22(1).
4.Tartaglione S , Pecorella I , Zarrillo S R , et al. Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study[J]. Biochemia Medica, 2019, 29(2).
Product detail pictures:
Related Product Guide:
With a positive and progressive attitude to customer's interest, our company continuously improves our product quality to meet the needs of customers and further focuses on safety, reliability, environmental requirements, and innovation of High Performance Test For Blood In Stool - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Slovak Republic, Lithuania, United States, "Good quality, Good service " is always our tenet and credo. We take every effort to control the quality, package, labels etc and our QC will check every detail during producing and before shipment. We have been willing to establish long business relationship with all those who seek the high quality products and good service. We've got set up a wide sales network across European countries, North of America, South of America, Middle East, Africa, East Asia countries.Please contact us now, you will find our expert experience and high quality grades will contribute to your business.
By Julia from Bangkok - 2017.05.02 18:28
In China, we have many partners, this company is the most satisfying to us, reliable quality and good credit, it is worth appreciation.
By Camille from Jordan - 2018.05.22 12:13
