High Quality for Direct Antibody Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody
High Quality for Direct Antibody Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody Detail:
Product details
General Information
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.
Properties
| Pair Recommendation |
CLIA (Capture-Detection): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | PBS, pH7.4 |
| Storage |
Store it under sterile conditions at -20℃ to -80℃ upon receiving. For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles. |
Comparison Analysis
| Bioantibody | clinically diagnosed case | Total | |
| positive | Negative | ||
| positive | 46 | 3 | 49 |
| Negative | 4 | 97 | 101 |
| Total | 50 | 100 | 150 |
| evaluation index | sensitivity | specificity | accuracy |
| 92% | 97% | 95% | |
Order Information
| Product Name | Cat. No | Clone ID |
| CHI3L1 | AB0031-1 | 1G11-14 |
| AB0031-2 | 2E4-2 | |
| AB0031-3 | 3A12-1 | |
| AB0031-4 | 13F3-1 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al. Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children[J]. Metabolism-clinical & Experimental, 2012, 61(4):562-568.
2.Yu-Huan M , Li-Ming T , Jian-Ying L I , et al. Evaluation on application of serum chitinase-3-like protein 1,alpha-fetoprotein and ferritin detection to diagnosing hepatocellular carcinoma[J]. Practical Preventive Medicine, 2018.
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Now we have highly developed devices. Our items are exported towards the USA, the UK and so on, enjoying a great popularity among the customers for High Quality for Direct Antibody Test - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody , The product will supply to all over the world, such as: Armenia, Australia, Turkey, We insist on "Quality First, Reputation First and Customer First". We are committed to providing high-quality products and good after-sales services. Up to now, our products have been exported to more than 60 countries and areas around the world, such as America, Australia and Europe. We enjoy a high reputation at home and abroad. Always persisting in the principle of "Credit, Customer and Quality", we expect cooperation with people in all walks of life for mutual benefits.
By Dinah from Hongkong - 2018.05.13 17:00
The product classification is very detailed that can be very accurate to meet our demand, a professional wholesaler.
By Nydia from Dubai - 2017.05.02 18:28
