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High reputation Malaria Antigen Test Kit - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody

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High reputation Malaria Antigen Test Kit - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

Properties

Pair Recommendation CLIA (Capture-Detection):
1D5-5 ~ 3G11-6
1D12-2 ~ 1G3-7
Purity >95% as determined by SDS-PAGE.
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
TIMP1 AB0034-1 1D5-5
AB0034-2 1D12-2
AB0034-3 1G3-7
AB0034-4 3G11-6

Note: Bioantibody can customized quantities per your need.

Citations

1.Barylski M , Kowalczyk E , Szadkowska I , et al. [Tissue inhibitor of metalloproteinases[J]. Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.

2.Hayakawa T , Yamashita K , Tanzawa K , et al. Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum[J]. FEBS Letters, 1992, 298.

3.Haider D G , Karin S , Gerhard P , et al. Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects.[J]. Journal of Clinical Endocrinology & Metabolism(3):1168-71.


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High reputation Malaria Antigen Test Kit - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures

High reputation Malaria Antigen Test Kit - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Our aim is usually to give superior quality items at aggressive rates, and top-notch company to clients around the earth. We have been ISO9001, CE, and GS certified and strictly adhere to their good quality specifications for High reputation Malaria Antigen Test Kit - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Florence, kazakhstan, Angola, We have established long-term, stable and good business relationships with many manufacturers and wholesalers around the world. Currently, we are looking forward to even greater cooperation with overseas customers based on mutual benefits. Please feel free to contact us for more details.
  • We have been cooperated with this company for many years, the company always ensure timely delivery ,good quality and correct number, we are good partners.
    5 Stars By Emma from Latvia - 2018.02.04 14:13
    The factory has advanced equipment, experienced staffs and good management level, so product quality had assurance, this cooperation is very relaxed and happy!
    5 Stars By Lee from Amsterdam - 2018.02.12 14:52
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