Hot New Products Pivka - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody

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continue to improve, to ensure product quality in line with market and customer standard requirements. Our company has a quality assurance system have been established for Pre Departure Antigen Test, In Vitro Rapid Diagnostic Test, Rapid Test Kit Antigen, We give priority to quality and customer satisfaction and for this we follow stringent quality control measures. We have in-house testing facilities where our products are tested on every aspect at different processing stages. Owning to latest technologies, we facilitate our customers with customized production facility.

Hot New Products Pivka - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Properties

Pair Recommendation	CLIA (Capture-Detection): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	PBS, pH7.4.
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name	Cat. No	Clone ID
GDF-15	AB0038-1	3A2-1
	AB0038-2	23F1-5
	AB0038-3	6C1-9
	AB0038-4	4D5-8

Note: Bioantibody can customized quantities per your need.

Citations

1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.

2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.

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