Hot sale Factory Rapid Test Antigen Swab - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody
Hot sale Factory Rapid Test Antigen Swab - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| Purity | >95% as determined by SDS-PAGE. |
| Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
| Bioantibody | Clinically Diagnosed Case | Total | |
| Positive | Negative | ||
| Positive | 35 | 0 | 35 |
| Negative | 1 | 87 | 88 |
| Total | 36 | 87 | 123 |
| Specificity | 100% | ||
| Sensitivity | 97% | ||
Order Information
| Product Name | Cat. No | Clone ID |
| IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.
2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.
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By Penny from Amman - 2017.07.07 13:00
The company can keep up with the changes in this industry market, product updates fast and the price is cheap, this is our second cooperation, it's good.
By Carol from Grenada - 2017.12.09 14:01
