• product_banner

Leading Manufacturer for Faecal Blood Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

Our team through professional training. Skilled professional knowledge, strong sense of service, to meet the service needs of customers for Trypsinogen-2, Test Rapid Antigen Saliva, Pregnancy Test Results, Our company has already set up a professional, creative and responsible team to develop clients with the multi-win principle.
Leading Manufacturer for Faecal Blood Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody Detail:

Product details

General Information
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.

Properties

Pair Recommendation CLIA (Capture-Detection):
1E5-1 ~ 1D6-10
1E5-1 ~ 1E6-7
Purity >95%, determined by SDS-PAGE
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

DETAIL (1)
DETAIL (2)

Order Information

Product Name Cat. No Clone ID
PIVKA-Ⅱ AB0009-1 1F4-5
AB0009-2 1E5-1
AB0009-3 1D6-10
AB0009-4 1E6-7

Note: Bioantibody can customized quantities per your need.

Citations

1.Matsueda K , Yamamoto H , Yoshida Y , et al. Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist II (PIVKA-II) and α-fetoprotein (AFP)[J]. Journal of Gastroenterology, 2006, 41(10):1011-1019.

2.Viggiani, Valentina, Palombi,等. Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients.[J]. Scandinavian Journal of Gastroenterology, 2016.

3.Simundic A M . Practical recommendations for statistical analysis and data presentation in Biochemia Medica journal[J]. Biochemia Medica, 2012, 22(1).

4.Tartaglione S , Pecorella I , Zarrillo S R , et al. Protein Induced by Vitamin K Absence II (PIVKA-II) as a potential serological biomarker in pancreatic cancer: a pilot study[J]. Biochemia Medica, 2019, 29(2).


Product detail pictures:

Leading Manufacturer for Faecal Blood Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures

Leading Manufacturer for Faecal Blood Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody detail pictures


Related Product Guide:

We're commitment to offer you the competitive price ,remarkable products excellent, also as fast delivery for Leading Manufacturer for Faecal Blood Test - Anti- human PIVKA -II Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Cologne, Singapore, Pretoria, With good quality, reasonable price and sincere service, we enjoy a good reputation. Products are exported to South America, Australia, Southeast Asia and so on. Warmly welcome customers at home and abroad to cooperate with us for the brilliant future.
  • Good quality, reasonable prices, rich variety and perfect after-sales service, it's nice!
    5 Stars By Adam from Poland - 2017.08.15 12:36
    Goods just received, we are very satisfied, a very good supplier, hope to make persistent efforts to do better.
    5 Stars By Lena from Rotterdam - 2018.05.22 12:13
    Write your message here and send it to us