Manufacturer for Antigen Test Kit - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody

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Manufacturer for Antigen Test Kit - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Properties

Pair Recommendation	CLIA (Capture-Detection): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1
Purity	>95% as determined by SDS-PAGE.
Buffer Formulation	20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

Bioantibody	Clinically Diagnosed Case		Total
Bioantibody	Positive	Negative	Total
Positive	35	0	35
Negative	1	87	88
Total	36	87	123
Specificity	100%
Sensitivity	97%

Order Information

Product Name	Cat. No	Clone ID
IGFBP-1	AB0028-1	4H6-2
	AB0028-2	4C2-3
	AB0028-3	2H11-1
	AB0028-4	3G12-11

Note: Bioantibody can customized quantities per your need.

Citations

1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.

2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.

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Our enterprise since its inception, constantly regards product good quality as organization life, constantly improve production technology, strengthen merchandise high quality and continuously strengthen enterprise total good quality administration, in strict accordance with all the national standard ISO 9001:2000 for Manufacturer for Antigen Test Kit - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Germany, United States, Turkey, Customer's satisfaction is always our quest, creating value for customers is always our duty, a long term mutual-beneficial business relationship is what we are doing for. We are an absolutely reliable partner for yourself in China. Of course, other services, like consulting, can be offered too.

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