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Manufacturer of H Pylori Antibodies In Blood - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody

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Manufacturer of H Pylori Antibodies In Blood - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody Detail:

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TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

Properties

Pair Recommendation CLIA (Capture-Detection):
1D5-5 ~ 3G11-6
1D12-2 ~ 1G3-7
Purity >95% as determined by SDS-PAGE.
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
TIMP1 AB0034-1 1D5-5
AB0034-2 1D12-2
AB0034-3 1G3-7
AB0034-4 3G11-6

Note: Bioantibody can customized quantities per your need.

Citations

1.Barylski M , Kowalczyk E , Szadkowska I , et al. [Tissue inhibitor of metalloproteinases[J]. Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.

2.Hayakawa T , Yamashita K , Tanzawa K , et al. Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum[J]. FEBS Letters, 1992, 298.

3.Haider D G , Karin S , Gerhard P , et al. Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects.[J]. Journal of Clinical Endocrinology & Metabolism(3):1168-71.


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Manufacturer of H Pylori Antibodies In Blood - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Manufacturer of H Pylori Antibodies In Blood - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Every single member from our higher effectiveness product sales staff values customers' requires and organization communication for Manufacturer of H Pylori Antibodies In Blood - Anti- human TIMP1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Peru, Gambia, Istanbul, With the development and enlargement of mass clients abroad, now we have set up cooperative relationships with many major brands. We have our own factory and also have many reliable and well-cooperated factories in the field. Adhering to the "quality first, customer first, We are provideing high-quality, low-cost products and first-class service to customers. We sincerely hope to establish business relationship with customers from all over the world on the basis of quality, mutually benefit. We welcome OEM projects and designs.
  • Managers are visionary, they have the idea of "mutual benefits, continuous improvement and innovation", we have a pleasant conversation and Cooperation.
    5 Stars By Iris from Colombia - 2017.01.11 17:15
    Sales manager is very enthusiastic and professional, gave us a great concessions and product quality is very good,thank you very much!
    5 Stars By Leona from Jakarta - 2018.06.21 17:11
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