• product_banner

Manufacturing Companies for Sflt-1 - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

We always continually offer you the most conscientious purchaser services, and the widest variety of designs and styles with finest materials. These efforts include the availability of customized designs with speed and dispatch for Self Antigen Test, Fecal Antigen Test, H Pylori Test Antibody, We, with great passion and faithfulness, are willing to provide you with perfect services and striding forward with you to create a bright future.
Manufacturing Companies for Sflt-1 - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody Detail:

Product details

General Information
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.

Properties

Pair Recommendation CLIA (Capture-Detection):
11G11-6 ~ 8A3-9
11G11-6 ~ 5B9-4
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

DETAIL (1)
DETAIL (2)

Order Information

Product Name Cat. No Clone ID
MMP-3 AB0025-1 11G11-6
AB0025-2 8A3-9
AB0025-3 5B9-4

Note: Bioantibody can customized quantities per your need.

Citations

1.Yamanaka H , Matsuda Y , Tanaka M , et al. Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritis[J]. Arthrits & Rheumatism, 2000, 43(4):852–858.

2.Hattori Y , Kida D , Kaneko A . Normal serum matrix metalloproteinase-3 levels can be used to predict clinical remission and normal physical function in patients with rheumatoid arthritis[J]. Clinical Rheumatology, 2018.


Product detail pictures:

Manufacturing Companies for Sflt-1 - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Manufacturing Companies for Sflt-1 - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody detail pictures


Related Product Guide:

The purchaser fulfillment is our primary focus on. We uphold a consistent level of professionalism, high quality, credibility and service for Manufacturing Companies for Sflt-1 - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Albania, Kazakhstan, Manila, With more than 9 years of experience and a professional team, we have exported our products to many countries and regions all over the world. We welcome customers, business associations and friends from all parts of the world to contact us and seek cooperation for mutual benefits.
  • The company's products very well, we have purchased and cooperated many times, fair price and assured quality, in short, this is a trustworthy company!
    5 Stars By Quyen Staten from United Arab Emirates - 2018.06.21 17:11
    Company director has very rich management experience and strict attitude, sales staff are warm and cheerful, technical staff are professional and responsible,so we have no worry about product,a nice manufacturer.
    5 Stars By Letitia from Puerto Rico - 2017.09.09 10:18
    Write your message here and send it to us