Massive Selection for In Vitro Rapid Diagnostic Test - Anti- human s100 β Antibody, Mouse Monoclonal – Bioantibody

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Massive Selection for In Vitro Rapid Diagnostic Test - Anti- human s100 β Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
S100B is a calcium binding protein, which is secreted from astrocytes. It is a small dimeric cytosolic protein (21 kDa) consisting of ββ or αβ chains. S100B is involved in a variety of intracellular and extracellular regulatory activities.
Over the last decade, S100B has emerged as a candidate peripheral biomarker of blood–brain barrier (BBB) damage and CNS injury. Elevated S100B levels accurately reflect the presence of neuropathological conditions including traumatic head injury and neurodegenerative diseases. Normal S100B levels reliably exclude major CNS pathology. Serum S100B has also been reported as a useful marker for early detection of metastases of melanoma and cerebral complications from head injury, cardiac surgery, and acute stroke.

Properties

Pair Recommendation	CLIA (Capture-Detection): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3
Purity	>95% as determined by SDS-PAGE.
Buffer Formulation	20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name	Cat. No	Clone ID
s100 β	AB0061-1	5H2-3
	AB0061-2	22G7-5
	AB0061-3	21A6-1

Note: Bioantibody can customized quantities per your need.

Citations

1. Ostendorp T , Leclerc E , Galichet A , et al. Structural and functional insights into RAGE activation by multimeric S100B[J]. The EMBO Journal, 2007, 26(16):3868-3878.

2. R, D, Rothoerl, et al. High serum S100B levels for trauma patients without head injuries.[J]. Neurosurgery, 2001.

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