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Massive Selection for Occult Blood Test Principle - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody

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Massive Selection for Occult Blood Test Principle - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Pepsinogen I, the precursors of pepsin, is produced by the gastric mucosa and released into the gastric lumen and peripheral circulation. Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kD. PG I (isoenzyme 1-5) is secreted mainly by chief cells in the fundic mucosa, whereas PG II (isoenzyme 6-7) is secreted by the pyloric glands and the proximal duodenal mucosa.
Precursor reflects numbers of stomach surface cells as well as glandular cells, and monitors gastric atrophy indirectly. They are also extraordinarily stable because they perform their jobs under the harsh conditions present in the digestive system. The atrophy of the corpus mucosa leads to low synthesis of pepsinogen I and hence its low release into the serum. Serum pepsinogen I indicates function and states of gastric mucosa.

Properties

Pair Recommendation CLIA (Capture-Detection):
1C1-3 ~ 1G7-3
1E3-1 ~ 1G7-3
Purity >95%, determined by SDS-PAGE
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

Comparison Analysis

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Order Information

Product Name Cat. No Clone ID
PGI AB0005-1 1C1-3
AB0005-2 1E3-1
AB0005-3 1G7-3

Note: Bioantibody can customized quantities per your need.

Citations

1.Sipponen P , Ranta P , Helske T , et al. Serum levels of amidated gastrin-17 and pepsinogen I in atrophic gastritis: an observational case-control study.[J]. Scandinavian Journal of Gastroenterology, 2002, 37(7):785-791.

2.Mangla J C , Schenk E A , Desbaillets L , et al. Pepsin secretion, pepsinogen, and gastrin in Barrett’s esophagus’. Clinical and morphological characteristics[J]. Gastroenterology, 1976, 70(5 PT.1):669-676.


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Our company promises all users of the first-class products and the most satisfying post-sale service. We warmly welcome our regular and new customers to join us for Massive Selection for Occult Blood Test Principle - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Iraq, Benin, Senegal, Our company abides by the management idea of "keep innovation, pursue excellence". On the basis of assuring the advantages of existing merchandise, we continuously strengthen and extend product development. Our company insists on innovation to promote the sustainable development of enterprise, and make us become the domestic high-quality suppliers.
  • Product quality is good, quality assurance system is complete, every link can inquire and solve the problem timely!
    5 Stars By Pearl Permewan from Qatar - 2017.08.16 13:39
    This company conforms to the market requirement and joins in the market competition by its high quality product, this is an enterprise that have Chinese spirit.
    5 Stars By Anna from Seattle - 2018.09.23 18:44
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