OEM Manufacturer Dengue Testing Kit - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody

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OEM Manufacturer Dengue Testing Kit - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.

Properties

Pair Recommendation	CLIA (Capture-Detection): 11G11-6 ~ 8A3-9 11G11-6 ~ 5B9-4
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	PBS, pH7.4.
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name	Cat. No	Clone ID
MMP-3	AB0025-1	11G11-6
	AB0025-2	8A3-9
	AB0025-3	5B9-4

Note: Bioantibody can customized quantities per your need.

Citations

1.Yamanaka H , Matsuda Y , Tanaka M , et al. Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritis[J]. Arthrits & Rheumatism, 2000, 43(4):852–858.

2.Hattori Y , Kida D , Kaneko A . Normal serum matrix metalloproteinase-3 levels can be used to predict clinical remission and normal physical function in patients with rheumatoid arthritis[J]. Clinical Rheumatology, 2018.

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Our target is to consolidate and improve the quality and service of existing products, meanwhile constantly develop new products to meet different customers' demands for OEM Manufacturer Dengue Testing Kit - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: UK, Surabaya, Johannesburg, Strong infrastructure is the need of any organization. We are backed with a robust infrastructural facility that enables us to manufacture, store, quality check and dispatch our products worldwide. To maintain smooth work flow, we have sectioned our infrastructure into a number of departments. All these departments are functional with latest tools, modernized machines and equipment. Owing to which, we are able to accomplish voluminous production without compromising upon the quality.

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