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OEM Manufacturer Dengue Testing Kit - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody

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General Information
Pepsinogen I, the precursors of pepsin, is produced by the gastric mucosa and released into the gastric lumen and peripheral circulation. Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kD. PG I (isoenzyme 1-5) is secreted mainly by chief cells in the fundic mucosa, whereas PG II (isoenzyme 6-7) is secreted by the pyloric glands and the proximal duodenal mucosa.
Precursor reflects numbers of stomach surface cells as well as glandular cells, and monitors gastric atrophy indirectly. They are also extraordinarily stable because they perform their jobs under the harsh conditions present in the digestive system. The atrophy of the corpus mucosa leads to low synthesis of pepsinogen I and hence its low release into the serum. Serum pepsinogen I indicates function and states of gastric mucosa.

Properties

Pair Recommendation CLIA (Capture-Detection):
1C1-3 ~ 1G7-3
1E3-1 ~ 1G7-3
Purity >95%, determined by SDS-PAGE
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
PGI AB0005-1 1C1-3
AB0005-2 1E3-1
AB0005-3 1G7-3

Note: Bioantibody can customized quantities per your need.

Citations

1.Sipponen P , Ranta P , Helske T , et al. Serum levels of amidated gastrin-17 and pepsinogen I in atrophic gastritis: an observational case-control study.[J]. Scandinavian Journal of Gastroenterology, 2002, 37(7):785-791.

2.Mangla J C , Schenk E A , Desbaillets L , et al. Pepsin secretion, pepsinogen, and gastrin in Barrett’s esophagus’. Clinical and morphological characteristics[J]. Gastroenterology, 1976, 70(5 PT.1):669-676.


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Our firm promises all consumers with the first-class products as well as most satisfying post-sale services. We warmly welcome our regular and new consumers to join us for OEM Manufacturer Dengue Testing Kit - Anti-human PGI Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Pretoria, Kuwait, Ecuador, Our product quality is one of the major concerns and has been produced to meet the customer's standards. "Customer services and relationship" is another important area which we understand good communication and relationships with our customers is the most significant power to run it as a long term business.
  • It is a very good, very rare business partners, looking forward to the next more perfect cooperation!
    5 Stars By Renee from Sevilla - 2017.10.13 10:47
    Customer service staff and sales man are very patience and they all good at English, product's arrival is also very timely, a good supplier.
    5 Stars By Ingrid from UK - 2018.09.19 18:37
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