OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody

Short Description:

Send email to us

Product Detail

Product Tags

Feedback (2)

Our primary objective is usually to offer our shoppers a serious and responsible small business relationship, offering personalized attention to all of them for Rapid Test In Vitro Diagnostic, Il-5 Protein, Rapid Dengue Test Ns1, We welcome you to inquire us by call or mail and hope to build a successful and cooperative relationship.

OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody Detail:

Product details

General Information
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.

Properties

Pair Recommendation	CLIA (Capture-Detection): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	PBS, pH7.4
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

Bioantibody	clinically diagnosed case		Total
Bioantibody	positive	Negative	Total
positive	46	3	49
Negative	4	97	101
Total	50	100	150
evaluation index	sensitivity	specificity	accuracy
evaluation index	92%	97%	95%

Order Information

Product Name	Cat. No	Clone ID
CHI3L1	AB0031-1	1G11-14
	AB0031-2	2E4-2
	AB0031-3	3A12-1
	AB0031-4	13F3-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al. Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children[J]. Metabolism-clinical & Experimental, 2012, 61(4):562-568.

2.Yu-Huan M , Li-Ming T , Jian-Ying L I , et al. Evaluation on application of serum chitinase-3-like protein 1,alpha-fetoprotein and ferritin detection to diagnosing hepatocellular carcinoma[J]. Practical Preventive Medicine, 2018.

Product detail pictures:

Related Product Guide:

Fast and great quotations, informed advisers to help you choose the correct solution that suits all your requirements, a short creation time, responsible top quality manage and distinct providers for paying and shipping affairs for OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody , The product will supply to all over the world, such as: Milan, Costa Rica, Danish, With all these supports, we can serve every customer with quality product and timely shipping with highly responsibility. Being a young growing company, we might not the best, but we're trying our best to be your good partner.

C Reactive Protein Normal Level