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OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody

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OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody Detail:

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General Information
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.

Properties

Pair Recommendation CLIA (Capture-Detection):
2E4-2 ~ 1G11-14
13F3-1 ~ 1G11-14
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

Bioantibody clinically diagnosed case Total
positive Negative
positive 46 3 49
Negative 4 97 101
Total 50 100 150
evaluation index sensitivity specificity accuracy
92% 97% 95%

Order Information

Product Name Cat. No Clone ID
CHI3L1 AB0031-1 1G11-14
AB0031-2 2E4-2
AB0031-3 3A12-1
AB0031-4 13F3-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al. Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children[J]. Metabolism-clinical & Experimental, 2012, 61(4):562-568.

2.Yu-Huan M , Li-Ming T , Jian-Ying L I , et al. Evaluation on application of serum chitinase-3-like protein 1,alpha-fetoprotein and ferritin detection to diagnosing hepatocellular carcinoma[J]. Practical Preventive Medicine, 2018.


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OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody detail pictures

OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody detail pictures


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The corporation upholds the philosophy of "Be No.1 in high quality, be rooted on credit rating and trustworthiness for growth", will continue to serve outdated and new consumers from home and overseas whole-heatedly for OEM Manufacturer Trypsin-2 - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody , The product will supply to all over the world, such as: Angola, Egypt, Montreal, We'd like to invite customers from abroad to discuss business with us. We can provide our clients with high quality products and excellent service. We are sure that we will have good cooperative relationships and make a brilliant future for both parties.
  • The customer service staff's attitude is very sincere and the reply is timely and very detailed, this is very helpful for our deal,thank you.
    5 Stars By Geraldine from panama - 2018.09.08 17:09
    Adhering to the business principle of mutual benefits, we have a happy and successful transaction, we think we will be the best business partner.
    5 Stars By Clara from Angola - 2017.06.29 18:55
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