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OEM Supply Il-6 - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody

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OEM Supply Il-6 - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension and proteinuria after 20 weeks of gestation. Preeclampsia occurs in 3‑5 % of pregnancies and results in substantial maternal and fetal or neonatal mortality and morbidity. Clinical manifestations can vary from mild to severe forms; preeclampsia is still one of the leading causes of fetal and maternal morbidity and mortality.

Preeclampsia appears to be due to the release of angiogenic factors from the placenta that induces endothelial dysfunction. Serum levels of PlGF (placental growth factor) and sFlt‑1 (soluble fms‑like tyrosine kinase‑1, also known as soluble VEGF receptor‑1) are altered in women with preeclampsia. Moreover, circulating levels of PlGF and sFlt‑1 can discriminate normal pregnancy from preeclampsia even before clinical symptoms occur. In normal pregnancy, the pro‑angiogenic factor PlGF increases during the first two trimesters and decreases as pregnancy progresses to term. In contrast, levels of the anti-angiogenic factor sFlt‑1 remain stable during the early and middle stages of gestation and increase steadily until term. In women who develop preeclampsia, sFlt‑1 levels have been found to be higher and PlGF levels have been found to be lower than in normal pregnancy.

Properties

Pair Recommendation  
CLIA (Capture-Detection):
7G1-2 ~ 5D9-3
5D9-3 ~ 7G1-2
Purity >95% as determined by SDS-PAGE.
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
PLGF AB0036-1 7G1-2
AB0036-2 5D9-3
AB0036-3 5G7-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Brown MA, Lindheimer MD, de Swiet M, et al. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 2001;20(1):IX-XIV.

2.Uzan J, Carbonnel M, Piconne O, et al. Pre-eclampsia: pathophysiology, diagnosis, and management. Vasc Health Risk Manag 2011;7:467-474.


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OEM Supply Il-6 - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody detail pictures

OEM Supply Il-6 - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody detail pictures


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We stay with our company spirit of "Quality, Performance, Innovation and Integrity". We goal to create more value for our clients with our abundant resources, advanced machinery, experienced workers and superb solutions for OEM Supply Il-6 - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Rwanda, The Swiss, Puerto Rico, We offer the great variety of products in this field. Besides, customized orders are also available. What's more, you will enjoy our excellent services. In one word, your satisfaction is guaranteed. Welcome to visit our company! For more information, please come to our website.If any further inquiries, please feel free to contact us.
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