Popular Design for In Vitro Diagnostic Use - Anti-human IL6 Antibody, Mouse Monoclonal – Bioantibody

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Popular Design for In Vitro Diagnostic Use - Anti-human IL6 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.

Properties

Pair Recommendation	CLIA (Capture-Detection): 1B1-4 ~ 2E4-1 2E4-1 ~ 1B1-4
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	PBS, pH7.4.
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

Correlation analysis-<120pg/mL

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Correlation analysis -1.5-5000pg/mL

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Order Information

Product Name	Cat. No	Clone ID
IL6	AB0001-1	1B1-4
	AB0001-2	2E4-1
	AB0001-3	2C3-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Zhong Z , Darnell Z W , Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6[J]. Science, 1994.

2.J, Bauer, F, et al. Interleukin-6 in clinical medicine[J]. Annals of Hematology, 1991.

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