Popular Design for In Vitro Diagnostic Use - Anti-human PG II Antibody, Mouse Monoclonal – Bioantibody

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General Information
Pepsinogen is the pro-form of pepsin and is produced in the stomach by chief cells. The major part of pepsinogen is secreted into the gastric lumen but a small amount can be found in the blood. Alterations in the serum pepsinogen concentrations has been found with Helicobacter pylori (H. Pylori) infections, peptic ulcer disease, gastritis, and gastric cancer. More precise analysis may be achieved by measuring the pepsinogen I/II ratio.

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Citations

1.Kodoi A , Haruma K , Yoshihara M , et al. [A clinical study of pepsinogen I and II producing gastric carcinomas].[J]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1993, 90(12):2971.

2.Xiao-Mei L , Xiu Z , Ai-Min Z . Clinical study of serum pepsinogen for the identification of gastric cancer and gastric precancerous lesions[J]. Modern Digestion & Intervention, 2017.