Popular Design for Malaria Diagnostic Test Kits - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody
Popular Design for Malaria Diagnostic Test Kits - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Properties
| Pair Recommendation | CLIA (Capture-Detection): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| Purity | >95% as determined by SDS-PAGE. |
| Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
| Bioantibody | Clinically Diagnosed Case | Total | |
| Positive | Negative | ||
| Positive | 35 | 0 | 35 |
| Negative | 1 | 87 | 88 |
| Total | 36 | 87 | 123 |
| Specificity | 100% | ||
| Sensitivity | 97% | ||
Order Information
| Product Name | Cat. No | Clone ID |
| IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.
2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.
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Innovation, quality and reliability are the core values of our company. These principles today more than ever form the basis of our success as an internationally active mid-size company for Popular Design for Malaria Diagnostic Test Kits - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Johannesburg, Greenland, Comoros, Our products have mainly exported to south-east Asia Euro-America, and sales to all of our country. And depending on excellent quality, reasonable price, best service, we have got good feedback from customers overseas. You are welcomed to join us for more possibilities and benefits. We welcome customers, business associations and friends from all parts of the world to contact us and seek cooperation for mutual benefits.
By Philipppa from Mali - 2017.04.18 16:45
It is really lucky to meet such a good supplier, this is our most satisfied cooperation, I think we will work again!
By Jodie from Malaysia - 2017.09.29 11:19
