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Anti-human PG II Antibody, Mouse Monoclonal
Product details General Information Pepsinogen is the pro-form of pepsin and is produced in the stomach by chief cells. The major part of pepsinogen is secreted into the gastric lumen but a small amount can be found in the blood. Alterations in the serum pepsinogen concentrations has been found with Helicobacter pylori (H. Pylori) infections, peptic ulcer disease, gastritis, and gastric cancer. More precise analysis may be achieved by measuring the pepsinogen I/II ratio. Properties Pair Re... -
Anti- human PIVKA -II Antibody, Mouse Monoclonal
Product details General Information Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinom... -
Anti- human s100 β Antibody, Mouse Monoclonal
Product details General Information S100B is a calcium binding protein, which is secreted from astrocytes. It is a small dimeric cytosolic protein (21 kDa) consisting of ββ or αβ chains. S100B is involved in a variety of intracellular and extracellular regulatory activities. Over the last decade, S100B has emerged as a candidate peripheral biomarker of blood–brain barrier (BBB) damage and CNS injury. Elevated S100B levels accurately reflect the presence of neuropathological conditions includi... -
Anti- human TIMP1 Antibody, Mouse Monoclonal
Product details General Information TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes wi... -
Anti-human MPO Antibody, Mouse Monoclonal
Product details General Information MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands. Myeloperoxidase (MPO), a specific p... -
Anti-human GDF15 Antibody, Mouse Monoclonal
Product details General Information Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathway... -
Anti- human Lp-PLA2 Antibody, Mouse Monoclonal
Product details General Information Lipoprotein-associated phospholipase A2 (Lp-PLA2) is produced by inflammatory cells and circulates primarily bound to low-density lipoprotein (LDL) and is to a lesser extent associated with high-density lipoprotein (HDL) in human plasma. LDL oxidation is known as an early key event in the pathogenesis of atherosclerosis. Elevated Lp-PLA2 levels have been found in atherosclerotic plaques and rupture lesions. Properties Pair Recommendation CLIA (Capture-De... -
Anti-human GH Antibody, Mouse Monoclonal
Product details General Information Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in human and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid,... -
Anti-human PRL Antibody, Mouse Monoclonal
Product details General Information Prolactin (PRL), also known as lactotropin, is a hormone made by the pituitary gland, a small gland at the base of the brain. Prolactin causes the breasts to grow and make milk during pregnancy and after birth. Prolactin levels are normally high for pregnant women and new mothers. Levels are normally low for nonpregnant women and for men. A prolactin levels test is most often used to: ★ Diagnose a prolactinoma (a type of tumor of the pituitary gland) ★ Help... -
Anti-human SHBG Antibody, Mouse Monoclonal
Product details General Information Sex hormone binding globulin (SHBG) is a glycoprotein of about 80-100 kDa; it has a high affinity for 17 beta-hydroxysteroid hormones such as testosterone and estradiol. SHBG concentration in plasma is regulated by, amongst other things, androgen/estrogen balance, thyroid hormones, insulin and dietary factors. It is the most important transport protein for estrogens and androgens in peripheral blood. SHBG concentration is a major factor regulating their dis... -
Anti-human calprotectin Antibody, Mouse Monoclonal
Product details General Information Calprotectin is a protein released by a type of white blood cell called a neutrophil. When there is inflammation in the gastrointestinal (GI) tract, neutrophils move to the area and release calprotectin, resulting in an increased level in the stool. Measuring the level of calprotectin in stool is a useful way to detect inflammation in the intestines. Intestinal inflammation is associated with inflammatory bowel disease (IBD) and with some bacterial GI infec... -
Anti-human IL6, Mouse Monoclonal
Product details General Information Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinas...