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Anti- human CHI3L1 Antibody, human Monoclonal
Product details General Information Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is abs... -
Anti-human Her2 Antibody, Mouse Monoclonal
Product details General Information Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-med... -
Anti-human PGI Antibody, Mouse Monoclonal
Product details General Information Pepsinogen I, the precursors of pepsin, is produced by the gastric mucosa and released into the gastric lumen and peripheral circulation. Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kD. PG I (isoenzyme 1-5) is secreted mainly by chief cells in the fundic mucosa, whereas PG II (isoenzyme 6-7) is secreted by the pyloric glands and the proximal duodenal mucosa. Precursor reflects numbers of stomac... -
Anti-human PG II Antibody, Mouse Monoclonal
Product details General Information Pepsinogen is the pro-form of pepsin and is produced in the stomach by chief cells. The major part of pepsinogen is secreted into the gastric lumen but a small amount can be found in the blood. Alterations in the serum pepsinogen concentrations has been found with Helicobacter pylori (H. Pylori) infections, peptic ulcer disease, gastritis, and gastric cancer. More precise analysis may be achieved by measuring the pepsinogen I/II ratio. Properties Pair Re... -
Anti- human PIVKA -II Antibody, Mouse Monoclonal
Product details General Information Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinom... -
Anti- human s100 β Antibody, Mouse Monoclonal
Product details General Information S100B is a calcium binding protein, which is secreted from astrocytes. It is a small dimeric cytosolic protein (21 kDa) consisting of ββ or αβ chains. S100B is involved in a variety of intracellular and extracellular regulatory activities. Over the last decade, S100B has emerged as a candidate peripheral biomarker of blood–brain barrier (BBB) damage and CNS injury. Elevated S100B levels accurately reflect the presence of neuropathological conditions includi... -
Anti- human TIMP1 Antibody, Mouse Monoclonal
Product details General Information TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes wi... -
Anti-human MPO Antibody, Mouse Monoclonal
Product details General Information MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands. Myeloperoxidase (MPO), a specific p... -
Anti-human GDF15 Antibody, Mouse Monoclonal
Product details General Information Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathway... -
Anti- human Lp-PLA2 Antibody, Mouse Monoclonal
Product details General Information Lipoprotein-associated phospholipase A2 (Lp-PLA2) is produced by inflammatory cells and circulates primarily bound to low-density lipoprotein (LDL) and is to a lesser extent associated with high-density lipoprotein (HDL) in human plasma. LDL oxidation is known as an early key event in the pathogenesis of atherosclerosis. Elevated Lp-PLA2 levels have been found in atherosclerotic plaques and rupture lesions. Properties Pair Recommendation CLIA (Capture-De... -
Anti-human GH Antibody, Mouse Monoclonal
Product details General Information Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in human and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid,... -
Anti-human PRL Antibody, Mouse Monoclonal
Product details General Information Prolactin (PRL), also known as lactotropin, is a hormone made by the pituitary gland, a small gland at the base of the brain. Prolactin causes the breasts to grow and make milk during pregnancy and after birth. Prolactin levels are normally high for pregnant women and new mothers. Levels are normally low for nonpregnant women and for men. A prolactin levels test is most often used to: ★ Diagnose a prolactinoma (a type of tumor of the pituitary gland) ★ Help...