Professional China Raw Materials - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody
Professional China Raw Materials - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension and proteinuria after 20 weeks of gestation. Preeclampsia occurs in 3‑5 % of pregnancies and results in substantial maternal and fetal or neonatal mortality and morbidity. Clinical manifestations can vary from mild to severe forms; preeclampsia is still one of the leading causes of fetal and maternal morbidity and mortality.
Preeclampsia appears to be due to the release of angiogenic factors from the placenta that induces endothelial dysfunction. Serum levels of PlGF (placental growth factor) and sFlt‑1 (soluble fms‑like tyrosine kinase‑1, also known as soluble VEGF receptor‑1) are altered in women with preeclampsia. Moreover, circulating levels of PlGF and sFlt‑1 can discriminate normal pregnancy from preeclampsia even before clinical symptoms occur. In normal pregnancy, the pro‑angiogenic factor PlGF increases during the first two trimesters and decreases as pregnancy progresses to term. In contrast, levels of the anti-angiogenic factor sFlt‑1 remain stable during the early and middle stages of gestation and increase steadily until term. In women who develop preeclampsia, sFlt‑1 levels have been found to be higher and PlGF levels have been found to be lower than in normal pregnancy.
Properties
| Pair Recommendation |
CLIA (Capture-Detection): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
| Purity | >95% as determined by SDS-PAGE. |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Order Information
| Product Name | Cat. No | Clone ID |
| PLGF | AB0036-1 | 7G1-2 |
| AB0036-2 | 5D9-3 | |
| AB0036-3 | 5G7-1 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Brown MA, Lindheimer MD, de Swiet M, et al. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 2001;20(1):IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, et al. Pre-eclampsia: pathophysiology, diagnosis, and management. Vasc Health Risk Manag 2011;7:467-474.
Product detail pictures:
Related Product Guide:
We have our own sales team, design team, technical team, QC team and package team. We have strict quality control procedures for each process. Also, all of our workers are experienced in printing field for Professional China Raw Materials - Anti-human PLGF Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Bangladesh, Philippines, Las Vegas, To have much more enterprise. ompanions, we've got updated the item list and seek for optimistic co-operation. Our web-site shows the latest and complete information and facts about our goods list and company. For further acknowledge, our consultant service group in Bulgaria will reply to all of the inquiries and complications immediately. They're going to make their finest effort to meet buyers need. Also we support the delivery of absolutely free samples. Business visits to our business in Bulgaria and factory are generally welcome for a win-win negotiation. Hope to expertise a happy company co-operation perform with you.
By Faithe from Oslo - 2018.05.13 17:00
Sales manager is very enthusiastic and professional, gave us a great concessions and product quality is very good,thank you very much!
By Julia from Dubai - 2017.06.19 13:51
