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Quality Inspection for In Vitro Diagnostic Solutions - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody

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Quality Inspection for In Vitro Diagnostic Solutions - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody Detail:

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General Information
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.

Properties

Pair Recommendation CLIA (Capture-Detection):
2E4-2 ~ 1G11-14
13F3-1 ~ 1G11-14
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
For long term storage, please aliquot and store it. Avoid repeated freezing and thawing cycles.

Comparison Analysis

Bioantibody clinically diagnosed case Total
positive Negative
positive 46 3 49
Negative 4 97 101
Total 50 100 150
evaluation index sensitivity specificity accuracy
92% 97% 95%

Order Information

Product Name Cat. No Clone ID
CHI3L1 AB0031-1 1G11-14
AB0031-2 2E4-2
AB0031-3 3A12-1
AB0031-4 13F3-1

Note: Bioantibody can customized quantities per your need.

Citations

1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al. Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children[J]. Metabolism-clinical & Experimental, 2012, 61(4):562-568.

2.Yu-Huan M , Li-Ming T , Jian-Ying L I , et al. Evaluation on application of serum chitinase-3-like protein 1,alpha-fetoprotein and ferritin detection to diagnosing hepatocellular carcinoma[J]. Practical Preventive Medicine, 2018.


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Quality Inspection for In Vitro Diagnostic Solutions - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody detail pictures

Quality Inspection for In Vitro Diagnostic Solutions - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody detail pictures


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Quality comes first; service is foremost; business is cooperation" is our business philosophy which is constantly observed and pursued by our company for Quality Inspection for In Vitro Diagnostic Solutions - Anti- human CHI3L1 Antibody, human Monoclonal – Bioantibody , The product will supply to all over the world, such as: Kuala Lumpur, New Zealand, Jamaica, Our company has built stable business relationships with many well-known domestic companies as well as oversea customers. With the goal of providing high quality products to customers at low cots, we are committed to improving its capacities in research, development, manufacturing and management. We have honored to receive recognition from our customers. Till now we have passed ISO9001 in 2005 and ISO/TS16949 in 2008. Enterprises of "quality of survival, the credibility of development" for the purpose, sincerely welcome domestic and foreign businessmen to visit to discuss cooperation.
  • The company comply with the contract strict, a very reputable manufacturers, worthy a long-term cooperation.
    5 Stars By Ivy from Latvia - 2018.05.13 17:00
    We are old friends, the company's product quality has been always very good and this time the price is also very cheap.
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