Short Lead Time for Chikungunya Igm Igg - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody
Short Lead Time for Chikungunya Igm Igg - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody Detail:
Product details
General Information
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.
Properties
| Pair Recommendation |
CLIA (Capture-Detection): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| Purity | >95%, determined by SDS-PAGE |
| Buffer Formulation | PBS, pH7.4. |
| Storage | Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. |
Competitive Comparison
Order Information
| Product Name | Cat. No | Clone ID |
| GDF-15 | AB0038-1 | 3A2-1 |
| AB0038-2 | 23F1-5 | |
| AB0038-3 | 6C1-9 | |
| AB0038-4 | 4D5-8 |
Note: Bioantibody can customized quantities per your need.
Citations
1.Wollert K C , Kempf T , Peter T , et al. Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non–ST-Elevation Acute Coronary Syndrome[J]. Circulation, 2007, 115(8):962-971.
2.Kempf T , Haehling S V , Peter T , et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure.[J]. Journal of the American College of Cardiology, 2007, 50(11):1054-1060.
Product detail pictures:
Related Product Guide:
We often persist with the theory "Quality To start with, Prestige Supreme". We are fully committed to delivering our clientele with competitively priced good quality items, prompt delivery and experienced support for Short Lead Time for Chikungunya Igm Igg - Anti-human GDF15 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Irish, Anguilla, Swaziland, Our team knows well the market demands in different countries, and is capable of supplying suitable quality products at the best prices to different markets. Our company has already set up a professional, creative and responsible team to develop clients with the multi-win principle.
By Prudence from Egypt - 2017.11.20 15:58
A nice supplier in this industry, after a detail and careful discussion, we reached a consensus agreement. Hope that we cooperate smoothly.
By Irma from Rwanda - 2017.10.23 10:29
