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Super Lowest Price Rapid Antigen Test Mechanism - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody

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Super Lowest Price Rapid Antigen Test Mechanism - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.

Properties

Pair Recommendation CLIA (Capture-Detection):
11G11-6 ~ 8A3-9
11G11-6 ~ 5B9-4
Purity >95%, determined by SDS-PAGE
Buffer Formulation PBS, pH7.4.
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

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Order Information

Product Name Cat. No Clone ID
MMP-3 AB0025-1 11G11-6
AB0025-2 8A3-9
AB0025-3 5B9-4

Note: Bioantibody can customized quantities per your need.

Citations

1.Yamanaka H , Matsuda Y , Tanaka M , et al. Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritis[J]. Arthrits & Rheumatism, 2000, 43(4):852–858.

2.Hattori Y , Kida D , Kaneko A . Normal serum matrix metalloproteinase-3 levels can be used to predict clinical remission and normal physical function in patients with rheumatoid arthritis[J]. Clinical Rheumatology, 2018.


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Super Lowest Price Rapid Antigen Test Mechanism - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Super Lowest Price Rapid Antigen Test Mechanism - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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The company keeps to the operation concept "scientific management, high quality and efficiency primacy, customer supreme for Super Lowest Price Rapid Antigen Test Mechanism - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Romania, Thailand, Monaco, We maintain long-term efforts and self-criticism, which helps us and improvement constantly. We strive to improve customer efficiency to save costs for customers. We do our best to improve the quality of product. We will not live up to the historic opportunity of the times.
  • The product classification is very detailed that can be very accurate to meet our demand, a professional wholesaler.
    5 Stars By Jean Ascher from Slovenia - 2017.10.13 10:47
    Good quality and fast delivery, it's very nice. Some products have a little bit problem, but the supplier replaced timely, overall, we are satisfied.
    5 Stars By David Eagleson from azerbaijan - 2018.09.19 18:37
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