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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody

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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Properties

Pair Recommendation CLIA (Capture-Detection):
4H6-2 ~ 4C2-3
4H6-2 ~ 2H11-1
Purity >95% as determined by SDS-PAGE.
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

Bioantibody Clinically Diagnosed Case Total
Positive Negative
Positive 35 0 35
Negative 1 87 88
Total 36 87 123
Specificity 100%
Sensitivity 97%

Order Information

Product Name Cat. No Clone ID
IGFBP-1 AB0028-1 4H6-2
AB0028-2 4C2-3
AB0028-3 2H11-1
AB0028-4 3G12-11

Note: Bioantibody can customized quantities per your need.

Citations

1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.

2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.


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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Our pursuit and firm aim should be to "Always fulfill our buyer requirements". We carry on to produce and structure top-quality excellent solutions for equally our aged and new consumers and accomplish a win-win prospect for our consumers as well as us for Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Czech republic, Turkey, Porto, With the aim of "compete with good quality and develop with creativity" and the service principle of "take customers' demand as orientation", we will earnestly provide qualified products and good service for domestic and international customers.
  • We are a small company that has just started, but we get the company leader's attention and gave us a lot of help. Hope we can make progress together!
    5 Stars By Austin Helman from Slovak Republic - 2018.05.15 10:52
    High Quality, High Efficiency, Creative and Integrity, worth having long-term cooperation! Looking forward to the future cooperation!
    5 Stars By Amelia from Kazakhstan - 2017.08.28 16:02
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