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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody

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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Properties

Pair Recommendation CLIA (Capture-Detection):
4H6-2 ~ 4C2-3
4H6-2 ~ 2H11-1
Purity >95% as determined by SDS-PAGE.
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

Bioantibody Clinically Diagnosed Case Total
Positive Negative
Positive 35 0 35
Negative 1 87 88
Total 36 87 123
Specificity 100%
Sensitivity 97%

Order Information

Product Name Cat. No Clone ID
IGFBP-1 AB0028-1 4H6-2
AB0028-2 4C2-3
AB0028-3 2H11-1
AB0028-4 3G12-11

Note: Bioantibody can customized quantities per your need.

Citations

1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.

2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.


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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Our advantages are reduced prices,dynamic product sales workforce,specialized QC,solid factories,superior quality services for Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: New York, United Kingdom, Bangladesh, With the goal of "zero defect". To care for the environment, and social returns, care employee social responsibility as own duty. We welcome friends from all over the world to visit and guide us so that we can achieve the win-win goal together.
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