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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody

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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody Detail:

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General Information
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor-binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Properties

Pair Recommendation CLIA (Capture-Detection):
4H6-2 ~ 4C2-3
4H6-2 ~ 2H11-1
Purity >95% as determined by SDS-PAGE.
Buffer Formulation 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4
Storage Store it under sterile conditions at -20℃ to -80℃ upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

Bioantibody Clinically Diagnosed Case Total
Positive Negative
Positive 35 0 35
Negative 1 87 88
Total 36 87 123
Specificity 100%
Sensitivity 97%

Order Information

Product Name Cat. No Clone ID
IGFBP-1 AB0028-1 4H6-2
AB0028-2 4C2-3
AB0028-3 2H11-1
AB0028-4 3G12-11

Note: Bioantibody can customized quantities per your need.

Citations

1.Rutanen E M . Insulin-like growth factor binding protein 1: US 1996.

2.Harman, S, Mitchell, et al. Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer[J]. Journal of Clinical Endocrinology & Metabolism, 2000.


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Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody detail pictures

Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody detail pictures


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Always customer-oriented, and it's our ultimate target to be not only the most reliable, trustable and honest supplier, but also the partner for our customers for Well-designed Tnfαprotein - Anti- human IGFBP-1 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Chile, America, Nepal, Insisting on the high quality generation line management and customers expert assistance, we now have designed our resolution to supply our buyers using the to start with amount getting and just after services practical experience. Maintaining the prevailing friendly relations with our buyers, we however innovate our solution lists all of the time to satisfy the brand new demands and adhere to the most up-to-date development of the market in Malta. We have been ready to face the worries and make the improve to understand all the possibilities in international trade.
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    We have been engaged in this industry for many years, we appreciate the work attitude and production capacity of the company, this is a reputable and professional manufacturer.
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