Wholesale Price Pregnancy - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody

Short Description:

Send email to us

Product Detail

Product Tags

Feedback (2)

Our mission is to become an innovative supplier of high-tech digital and communication devices by providing value added design, world-class manufacturing, and service capabilities for Abnormal Occult Blood Test, Flu B, Pylori Antibody, "Making the Products of High Quality" is the eternal goal of our company. We make unremitting efforts to realize the goal of "We Will Always Keep in Pace with the Time".

Wholesale Price Pregnancy - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody Detail:

Product details

General Information
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.

Properties

Pair Recommendation	CLIA (Capture-Detection): 11G11-6 ~ 8A3-9 11G11-6 ~ 5B9-4
Purity	>95%, determined by SDS-PAGE
Buffer Formulation	PBS, pH7.4.
Storage	Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

Competitive Comparison

DETAIL (1)
DETAIL (2)

Order Information

Product Name	Cat. No	Clone ID
MMP-3	AB0025-1	11G11-6
	AB0025-2	8A3-9
	AB0025-3	5B9-4

Note: Bioantibody can customized quantities per your need.

Citations

1.Yamanaka H , Matsuda Y , Tanaka M , et al. Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritis[J]. Arthrits & Rheumatism, 2000, 43(4):852–858.

2.Hattori Y , Kida D , Kaneko A . Normal serum matrix metalloproteinase-3 levels can be used to predict clinical remission and normal physical function in patients with rheumatoid arthritis[J]. Clinical Rheumatology, 2018.

Product detail pictures:

Related Product Guide:

We now have a skilled, performance team to supply good quality services for our consumer. We often follow the tenet of customer-oriented, details-focused for Wholesale Price Pregnancy - Anti-human MMP-3 Antibody, Mouse Monoclonal – Bioantibody , The product will supply to all over the world, such as: Russia, Serbia, Suriname, Since the establishment of our company, we've realized the importance of providing good quality goods and the best before-sales and after-sales services. Most problems between global suppliers and clients are due to poor communication. Culturally, suppliers can be reluctant to question points they do not understand. We break down these barriers to ensure you get what you want to the level you expect, when you want it.

Antigen Test In Vitro